Tissues and Biomaterial Research Group-(TBRG)Journal of Bioengineering Research2645-56332420201204Study of Genes Associated With Parkinson Disease Using Feature Selection11111974510.22034/jbr.2020.251812.1035ENHoda RafieipourDepartment of Computer Science, Memorial University of Newfoundland, NF, CanadaAzadeh Abdollah ZadehDepartment of Computer and Electrical Engineering and Computer Science, Florida Atlantic University, Boca Raton, FL, USA0000-0002-5962-119XAtefeh MoradanDepartment of Computer Science, Aarhus University, Aarhus, DenmarkZahra SalekshahrezaeeDepartment of Computer and Electrical Engineering and Computer Science, Florida Atlantic University, FL, USA0000-0003-0734-0983Journal Article20201019The second most prevalent age-related neurodegenerative disease is Parkinson's (PD) and Genes associated with human diseases like Parkinson are descriptive. Genome-wide association study (GWAS) is used to classify the genes associated with Parkinson’s and other diseases. The information of identified genes empowers scientists to early diagnose, treat, and sop diseases. Due to the complexities of the illness, identifying such genes is a challenging task. In this article, we apply two methods of feature selection to choose a subset of genes that are used to predict PD with high precision in classification. The chromosome corresponding to selected features is analyzed by Perturbation-based Feature Selection (PFS) and Hilbert-Schmidt independence criterion (HSIC)-Lasso. These algorithms are used to identify how chromosomes play an important role with respect to PD. We used a dataset consist of 50 predominantly patients gene expression profiles with early-stage Parkinson's disease (PD) and 55 normal GEO samples. These methods provide a series of features involved in disease-specific processes that are applied to prioritize candidate genes in GWAS loci.Tissues and Biomaterial Research Group-(TBRG)Journal of Bioengineering Research2645-56332420201231A Portable Motion Sensor to Measure the Movements of Runners for Biomechanics Analysis122211974810.22034/jbr.2020.253869.1036ENElham ZareFaculty of Science and Medical Technologies, Islamic Azad University, Science and Research Branch of Tehran, Tehran, IranSeyed Mohsen MohammadiDepartment of Mathematics, Faculty of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.Reza Abbasi KesbiMEMS & NEMS Laboratory, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran0000-0001-5726-5315Journal Article20201028Learning the activities of professional runners has always been very important for researchers because it leads to learning their movements by amateurs. Therefore, learning and recording movements accurately help to learn amateurs. In this paper, a portable system to record the obtained data of runners is presented. The presented system consists of an accelerometer and gyroscope sensor, a Bluetooth module as well as a processor that the data of three-dimensional angular velocity and linear acceleration sensors are read and recorded with the help of the small processor. This data is then stored in the processor and then sent to a Bluetooth module through the UART protocol. The data are sent to a personal computer for recording and simulation. The data are read using Matlab software and then illustrated. The results show that this system measures motion parameters for runners and can be calculated steps of movement. Additionally, the outcome result can be compared with professional runners by the amateurs for learning. The presented system is very small and inexpensive that can be easily used to record the activities among amateurs and improve their movements.Tissues and Biomaterial Research Group-(TBRG)Journal of Bioengineering Research2645-56332420201101The Effect of EMS on Strength of Biceps Brachii Muscle233211974610.22034/jbr.2020.245454.1029ENMohammad NajafiFaculty of Science and Medical Technologies, Islamic Azad University, Science and Research Branch of Tehran, Tehran, Iran.Siamak KhorramymehrFaculty of Science and Medical Technologies, Islamic Azad University, Science and Research Branch of Tehran, Tehran, Iran.Koorosh NakhaeiFaculty of Engineering, Department of Biomedical Engineering, Islamic Azad University, Islamshahr Branch, Islamshahr, Tehran, Iran.Journal Article20200827The method of electrical muscle stimulation (EMS) method, which is defined as the contraction of muscles by the creation of internal electrical stimuli, is used to increase the strength and volume of athletes' muscles in order to increase their performance. EMS has gained a lot of attention in recent years and can be used as a strength training tool for healthy people. EMS can be used as a test tool to assess neuro or muscular functions in vivo. In this paper, the effect of using the EMS method to strengthen muscle fibers is investigated by training the biceps brachii muscle. For this purpose, after studying many volunteers, 12 of them were selected and the strength of their biceps brachii muscles evaluated by a dynamometer before and after the EMS. The obtained results show that the biceps brachii muscle strength significantly increases in the volunteers after training by EMS for a duration of two weeks.Tissues and Biomaterial Research Group-(TBRG)Journal of Bioengineering Research2645-56332420201230Developing an In-expensive Device for Measuring the Pressure of Children's Soles334111974710.22034/jbr.2020.245574.1030ENMohammad NajafiFaculty of Science and Medical Technologies, Islamic Azad University, Science and Research Branch of Tehran, Tehran, Iran.Atefeh ValipourDepartment of Biomedical Engineering, Faculty of Medical Sciences and Technologies, Islamic Azad University Science and Research Branch, Tehran, Iran,Seyed Mohsen MohammadiDepartment of Mathematics, Faculty of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.Journal Article20200929Walking is one of the most necessary and important movements among humans, especially children. Walking problems can have serious consequences for children at an older age. In this paper, a system is developed that can show the pressure on the soles of children's feet. With this device, children's walking problems can be solved to a high extent. First, the weight sensor information is amplified with the help of an op-amp, and then it is read through an analog-to-digital converter, and with the help of this analog-to-digital converter, it is digitized. As it turns out, sensors have to translate information into machine language in order to transmit information, which can be done with the help of an analog-to-digital converter. After the micro converts this data to digital, the system is then calibrated and the calibrated data is sent to the computer via the UART protocol using a TTL to USB converter. This data is displayed on the computer for further review.Tissues and Biomaterial Research Group-(TBRG)Journal of Bioengineering Research2645-563324202012013D Bioprinting for Bone and Cartilage Tissue Engineering.11974910.22034/jbr.2020.119749ENJournal Article20201127