Control of delayed nonlinear model of type 1 diabetes using an improved sliding model strategy

Document Type : Original Article


1 West Virginia University, Department of Electrical and Computer, Morgantown, USA

2 Department of Electrical and Computer, Science and Research Branch, Islamic Azad University

3 Department of Electrical and Computer, Science and Research Branch, Islamic Azad University, Tehran, Iran



Diabetes has been identified as the sixth leading cause of death in the world. For this reason, diabetes is one of the new and important topics in control science. The goal of diabetes control and treatment is to keep blood glucose at a normal level in the body. Insulin must be injected into the body to control blood glucose in type 1 diabetes. It is so obvious that this injection must be completely controlled. Because an excessive increase in insulin injection can cause human death. In fact, it is not possible to generalize many common controllers for latency systems to delayed systems, and researchers are studying ways to design these controllers for delayed systems. In general, the number of differential equations is reduced in expressing the system behaviors in a delayed nonlinear form, while the method of controlling them will be much more complex. In this paper, the improved sliding mode control technique is used. The proposed improved sliding mode controller is suitable for pumping and delivering insulin in the closed-loop control of diabetes. The optimal insulin injection rate is obtained as a control signal for reference glucose tracking. Then, simulation results are observed to optimally track the patient's blood glucose in exchange for the optimal insulin injection rate. One of the advantages of the proposed method is high accuracy in the presence of physical disturbance such as food acceptance and uncertainty and its resistance.


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